Growth Hormone Research

GHRP-2 Research Guide

5mg · Research compound — not for human consumption

Research Overview

GHRP-2, also known as pralmorelin, is a synthetic hexapeptide of the growth-hormone-releasing peptide family that has been studied for its interaction with the ghrelin/growth-hormone-secretagogue receptor. It has been used as a research compound and has a documented history as a diagnostic agent in some jurisdictions. This material is intended for laboratory research only and is not intended for human consumption.

Structural & Class Overview

A synthetic hexapeptide (sequence commonly written D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2) incorporating D-amino acids that research associates with resistance to enzymatic degradation. It is classified as a high-affinity agonist of the growth-hormone-secretagogue receptor subtype 1a (GHS-R1a), mimicking ghrelin rather than acting through the GHRH receptor.

General Research Interest

Research interest includes GHS-R1a binding affinity and potency comparisons within the GHRP class; calcium-dependent signaling in growth-hormone release; interactions with the somatostatin pathway; growth-hormone-axis regulation in preclinical models; and inflammatory-signaling studies in cellular models.

Storage Considerations

Store the lyophilized research peptide cool and dark, and protect from light, heat, and moisture. Reconstituted material is generally handled under refrigeration for laboratory use. For research handling only; not for human use.

Testing & Quality Considerations

Quality considerations for research material include HPLC purity assessment, mass-spectrometry identity confirmation, and verification against a batch Certificate of Analysis (COA).

References

  1. GHRP-2 Attenuation of PKC-Induced Inflammation in Human Ovarian Granulosa Cells (PMC)
  2. Growth hormone secretagogues: history, mechanism of action, and clinical development (Wiley)

References are provided for scientific context. Linked sources are independent and not affiliated with iNGEN MD.

Research Use Only — Not For Human Consumption. All products sold by iNGEN MD are intended strictly for in-vitro laboratory and scientific research purposes only. These products are not approved by the FDA and are not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. By purchasing, you confirm you are a qualified researcher aged 18 or older, acting in compliance with all applicable laws. iNGEN MD assumes no liability for misuse.