Recovery Research

TB-500 Research Guide

5mg · Research compound — not for human consumption

Research Overview

TB-500 is a synthetic peptide fragment modeled on Thymosin Beta-4 (Tbeta4), a naturally occurring 43-amino-acid actin-binding protein. It has been studied in preclinical and in vitro settings for its role in actin regulation and cell-migration models. TB-500 is not FDA-approved and is presented here solely as a research compound not intended for human consumption.

Structural & Class Overview

Synthetic peptide fragment derived from the Thymosin Beta-4 sequence; the parent Tbeta4 is a G-actin-sequestering peptide (parent PubChem CID 45382195). Mechanistically classed among actin-modulating/cytoskeletal-remodeling peptides that interact with globular (G) actin and influence the G-actin/F-actin equilibrium.

General Research Interest

Research interest includes G-actin sequestration and cytoskeletal-remodeling dynamics; endothelial cell organization and migration in wound-model assays; angiogenesis-related actin-binding protein expression; and tissue-repair signaling explored across preclinical injury models. These represent laboratory study areas, not established human benefits.

Storage Considerations

General research-handling notes for a lyophilized peptide: keep the sealed lyophilized material cold, dry, and protected from light per supplier documentation; after reconstitution for laboratory use, refrigerate and limit freeze-thaw cycles. For laboratory settings only. Not intended for human consumption.

Testing & Quality Considerations

Quality considerations include HPLC purity analysis, mass-spectrometry confirmation of identity and molecular mass, and review of a batch-specific Certificate of Analysis (COA) prior to research use.

References

  1. Thymosin Beta 4 — PubChem CID 45382195
  2. Nuclear localisation of the G-actin sequestering peptide thymosin beta4 (PubMed)
  3. Thymosin beta 4 and Fx, an actin-sequestering peptide (PubMed)

References are provided for scientific context. Linked sources are independent and not affiliated with iNGEN MD.

Research Use Only — Not For Human Consumption. All products sold by iNGEN MD are intended strictly for in-vitro laboratory and scientific research purposes only. These products are not approved by the FDA and are not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. By purchasing, you confirm you are a qualified researcher aged 18 or older, acting in compliance with all applicable laws. iNGEN MD assumes no liability for misuse.