Cognitive / Longevity Research

Pinealon Research Guide

Research Overview

Pinealon is a synthetic tripeptide (Glu-Asp-Arg, EDR) in the short-peptide bioregulator class associated with the Khavinson research group. Public research information on this compound is limited. This page will be expanded as additional documentation is reviewed. This is a research compound not intended for human consumption.

Structural & Class Overview

Synthetic tripeptide, sequence glutamic acid-aspartic acid-arginine (Glu-Asp-Arg / EDR); part of the short-peptide bioregulator family. Proposed mechanism class studied in laboratory settings involves direct peptide-DNA/chromatin interaction and tissue-specific modulation of gene transcription rather than classical membrane-receptor binding.

General Research Interest

Research interest includes suppression of reactive oxygen species (ROS) accumulation in cultured rat cerebellar granule cells; modulation of cell-cycle markers (PCNA, p21) in neuronal cultures; proposed transcriptional regulation of antioxidant and neurotrophic genes; and studies in induced-neuron and neuroregeneration models.

Storage Considerations

General handling for a lyophilized research peptide: store lyophilized powder frozen, protected from light and moisture; refrigerate after reconstitution and avoid repeated freeze-thaw cycles. For laboratory research use only.

Testing & Quality Considerations

Quality considerations include HPLC purity assessment, mass spectrometry for identity confirmation, and review of a batch-specific Certificate of Analysis (COA).

References

  1. EDR Peptide: Mechanism of Gene Expression and Protein Synthesis Regulation (PMC)

References are provided for scientific context. Linked sources are independent and not affiliated with iNGEN MD.

Research Use Only — Not For Human Consumption. All products sold by iNGEN MD are intended strictly for in-vitro laboratory and scientific research purposes only. These products are not approved by the FDA and are not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. By purchasing, you confirm you are a qualified researcher aged 18 or older, acting in compliance with all applicable laws. iNGEN MD assumes no liability for misuse.