Cognitive / Longevity Research

Semax Research Guide

5mg · Research compound — not for human consumption

Research Overview

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH), developed to retain neurotropic signaling characteristics without hormonal adrenal activity. Preclinical research has explored its neuroprotective and neurotrophic-associated mechanisms in laboratory models. This is a research compound not intended for human consumption.

Structural & Class Overview

Synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro; CAS 80714-61-0). Hybrid structure combining the ACTH(4-7) fragment at the N-terminus with a C-terminal Pro-Gly-Pro tripeptide added for metabolic stability. Studied as a neuromodulatory/neurotrophic-associated peptide class agent.

General Research Interest

Research interest includes BDNF-associated signaling changes in preclinical models; transcriptional and gene-expression profiling in cerebral ischemia-reperfusion rat models; immunomodulatory and vascular gene expression in brain tissue; neuroprotection studies in laboratory ischemia models; and mechanistic proteomic analyses.

Storage Considerations

General handling for a lyophilized research peptide: keep lyophilized powder frozen, sealed, and protected from light; refrigerate after reconstitution and limit freeze-thaw cycles. For laboratory research use only.

Testing & Quality Considerations

Quality considerations include HPLC purity analysis, mass spectrometry for identity confirmation, and verification against a batch-specific Certificate of Analysis (COA).

References

  1. Semax affects expression of immune and vascular system genes in rat brain focal ischemia (PMC)
  2. Brain Protein Expression Profile of the ACTH(4-7)PGP Peptide (Semax) (PMC)

References are provided for scientific context. Linked sources are independent and not affiliated with iNGEN MD.

Research Use Only — Not For Human Consumption. All products sold by iNGEN MD are intended strictly for in-vitro laboratory and scientific research purposes only. These products are not approved by the FDA and are not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. By purchasing, you confirm you are a qualified researcher aged 18 or older, acting in compliance with all applicable laws. iNGEN MD assumes no liability for misuse.