Peptide Research

MOTS-c Research Guide

10mg · Research compound — not for human consumption

Research Overview

MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA region. Preclinical research has explored its role in cellular metabolic signaling and mitochondrial stress-response pathways in laboratory settings. This is a research compound not intended for human consumption.

Structural & Class Overview

A 16-amino-acid mitochondrial-derived peptide (MDP) encoded by a short open reading frame within the mitochondrial 12S rRNA gene. Mechanistically studied as a regulator of the AICAR-AMPK signaling axis and folate-methionine cycle, placing it in the metabolic-regulatory peptide class.

General Research Interest

Research interest includes activation of AMPK signaling and glucose-uptake pathways in skeletal muscle models; insulin-sensitivity and plasma-metabolite regulation in animal studies; exercise-associated changes in MOTS-c levels; mitochondrial respiration in metabolic-disorder models; and aging-associated mitochondrial biology.

Storage Considerations

General handling for a lyophilized research peptide: store lyophilized powder frozen, sealed, and protected from light; refrigerate after reconstitution and limit freeze-thaw cycles. For laboratory research use only.

Testing & Quality Considerations

Quality considerations include HPLC purity assessment, mass spectrometry for identity confirmation, and review of a batch-specific Certificate of Analysis (COA).

References

  1. MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation (PMC)
  2. The mitochondrial-derived peptide MOTS-c enhances insulin sensitivity (PMC)

References are provided for scientific context. Linked sources are independent and not affiliated with iNGEN MD.

Research Use Only — Not For Human Consumption. All products sold by iNGEN MD are intended strictly for in-vitro laboratory and scientific research purposes only. These products are not approved by the FDA and are not intended for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. By purchasing, you confirm you are a qualified researcher aged 21 or older, acting in compliance with all applicable laws. iNGEN MD assumes no liability for misuse.